I originally posted the audio from this NPR interview with Dr. John Piper on August 7, 2008, but I thought it was especially timely in relation to the recent disaster in Haiti and wanted to make it available again. This is a thoughtful, biblical response to people that question the sovereignty of God in the face of tragic events, in this case the subject of the interview was the 2005 Tsunami. The interview is about 30 minutes long but well worth the investment of time.
Related: You can download or listen to the interview at Desiring God.